Organic Syntheses, Coll. Vol. 1, p.175 (1941); Vol. 3, p.37 (1923).
One kilogram of technical sodium hydroxide
and .400 g. of technical potassium hydroxide (Note 1)
are melted together in a cast-iron flat-bottomed kettle, 18 cm. in depth and 18 cm. in diameter
. The fused mass is well stirred by means of a piece of iron pipe closed at one end
, containing a thermometer
; the hand is protected by a rubber glove
wrapped with a cloth. The temperature of the fused mass is allowed to fall to 230°, and 150 g. (0.73 mole) of technical sodium p-toluenesulfonate (Note 2)
is stirred in. The temperature is now slowly raised while 450 g. (2.2 moles) more of sodium p-toluenesulfonate
is added slowly, the additions being made whenever the melt becomes sufficiently thin to stir in the solid. When all has been added, the temperature should be about 270°; the addition requires about thirty minutes. The temperature is now raised to 300°, with occasional stirring. At this point there is a layer of heavy froth on the surface of the thin melt, and as the temperature rises this is stirred in, the whole melt becoming frothy and showing a tendency to foam over. On continuing to raise the temperature, the foaming suddenly disappears at about 330°; the melt becomes dark and evolution of hydrogen
sets in. The mixture is now thin and of uniform consistency; it is poured at once into an iron tray
and allowed to cool.
The solidified product is dissolved in 6-7 l. of water in a 12-l. flask
, and a solution of concentrated (95 per cent) sulfuric acid (about 880 cc.)
in about 2 l. of water is added until the liquor has a distinct odor of sulfur dioxide
. The heat of neutralization is sufficient to cause the solution to boil; it is at once distilled in a current of steam (Note 3)
until a sample of the distillate gives only a slight precipitate with bromine water
. The distillate (about 6–7 l.) is saturated with salt and the oil separated. The watery solution may be again distilled with steam in order to recover the small amount of cresol
in solution. The oil is at once distilled under reduced pressure, and the fraction which boils at 95–96° /15 mm.
is collected. The forerun is freed of water and redistilled, yielding a further quantity. On cooling, the product solidifies to a white, crystalline mass melting at 31° (Note 4)
. The yield is 200–230 g.
per cent of the theoretical amount based on sodium p-toluenesulfonate of 95 per cent
Technical sodium p-toluenesulfonate is, as a rule, of about 95 per cent
purity; it contains about 2 per cent of sodium chloride
and some moisture. Attempts to prepare a p-cresol
of higher melting point by fusion of recrystallized sodium p-toluenesulfonate
(which should presumably contain no isomers) have failed; it has been found impossible to raise the melting point above 31.4°.
Since distillation in a current of steam in a laboratory is apt to be a tedious process when only the regular form of Liebig condenser
is employed, much time can be saved by the use of the apparatus described on p. 479
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